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SSRI-associated nocturnal bruxism
in four patients.
Ellison JM, Stanziani
Department of Psychiatry, Tufts/New England Medical
Center, Boston, Mass. 02111.
BACKGROUND: Nocturnal bruxism (tooth
clenching and/or grinding during sleep) affects a significant proportion
of the population. Its etiology remains uncertain, and no entirely
satisfactory treatment is available. METHOD: This is an observational
report of four depressed individuals selected from one psychiatrist's
practice within an urban hospital's psychopharmacology clinic.
Psychiatric diagnoses were made according to DSM-III-R criteria.
Nocturnal bruxism was determined on the basis of dental examination
and/or self-reported nocturnal tooth clenching and/or grinding. RESULTS:
Four patients developed nocturnal bruxism within 2 to 4 weeks after
initiation of treatment with fluoxetine or sertraline. Bruxism remitted
in all patients after a decrease in antidepressant dosage (N = 1) or
addition of buspirone (N = 3). CONCLUSION: These observations, which
should be confirmed by a controlled study, suggest an association
between serotonin selective reuptake inhibitor (SSRI) treatment and the
onset or exacerbation of nocturnal bruxism. In addition, they suggest
that a decrease in SSRI dosage or the addition of buspirone may relieve
SSRI-associated nocturnal bruxism.
PMID: 8270587 [PubMed - indexed for