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[Adverse effects of selective
serotonin uptake inhibitors. Hyponatremia caused by Schwartz-Bartter
[Article in Danish]
Sorensen HA, Almdal TP.
H:S Hvidovre Hospital, medicinsk
This report describes three cases of
hyponatraemia/syndrome of inappropriate secretion of antidiuretic
hormone. The cases are most likely caused by treatment/intoxication with
three different selective serotonin reuptake inhibitors: Fluoxetine,
paroxetine and citalopram. All three patients were elderly women (75-83
years). Serum sodium values returned to normal or near normal after
discontinuation of the drug and concomitant fluid restriction.
Hyponatraemia has previously been described as an adverse effect to
fluoxetine and paroxetine, but not to citalopram.
PMID: 8984756 [PubMed - indexed for