Summary Brief Abstract Citation ASN.1 MEDLINE XML UI List LinkOut Related Articles Cited in Books Domain Links 3D Domain Links GEO DataSet Links Gene Links Genome Links GEO Links Nucleotide Links OMIM Links PMC Links Cited in PMC PopSet Links Protein Links SNP Links Structure Links UniSTS Links  Show: 5 10 20 50 100 200 500 Sort Author Journal Pub Date Text File Clipboard E-mail Order

1: Hum Exp Toxicol. 1999 May;18(5):309-13.

Related Articles, Links

Cardiovascular and neurological toxicity of venlafaxine.

Blythe D, Hackett LP.

Intensive Care Unit, Sir Charles Gairdner Hospital, Perth, Western Australia.

1. We report a case of venlafaxine overdose and describe pharmacokinetic data on drug disposition. 2. Case report. Serial venlafaxine levels were measured and drug half-life calculated and compared to data at therapeutic concentrations. Metabolite concentrations were also measured and the potential for toxicity described with reference to individual variation in such metabolism 3. Venlafaxine can cause significant cardiac and neurotoxicity. Its potential for causing such toxicity may be dependent on whether an individual has the extensive metaboliser cytochrome CYP2D6 phenotype or the poor metaboliser phenotype

Publication Types:

• Case Reports

PMID: 10372752 [PubMed - indexed for MEDLINE]

Jan 29 2004 15:06:34