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Comment in:
[Withdrawal
symptoms in a neonate following exposure to venlafaxine during
pregnancy]
[Article in Dutch]
de Moor RA,
Mourad L, ter Haar J, Egberts AC.
Afd. Kindergeneeskunde,
TweeSteden ziekenhuis, Postbus 90.107, 5000 LA Tilburg.
rdmoor@tsz.nl
Withdrawal symptoms occurred in a male neonate
after maternal use of venlafaxine for depression during pregnancy. The
symptoms were restlessness, hypertonia, jitteriness, irritability and
poor feeding. The diagnosis was confirmed by a temporary improvement
after administration of a low dose (1 mg) of venlafaxine to the boy.
Eventually the symptoms began to decline spontaneously, and ceased after
8 days. Exposure to venlafaxine and other antidepressants which inhibit
serotonin reuptake during the third trimester of pregnancy carries the
risk of a neonatal withdrawal syndrome.
Publication Types:
PMID: 12892015 [PubMed - indexed for
MEDLINE]
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