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1: Anasthesiol Intensivmed Notfallmed Schmerzther. 2001 Mar;36(3):184-7. Related Articles, Links

[A patient with nodal tachycardia after general anesthesia during medication with a selective serotonin reuptake inhibitor]

[Article in German]

Kopp R, Kunitz O, Baumert JH, Rossaint R.

Klinik fur Anasthesiologie des Universitatsklinikums der RWTH Aachen.

We report on a 62 year old female patient treated with paroxetine, a selective serotonin reuptake inhibitor, because of an anxiety neurosis undergoing a vaginal hysterectomy in general anesthesia. Apart from a dietary treated diabetes mellitus there were no other diseases. There were no complications during the operation. At the end of the anesthesia an A-V nodal tachycardia appeared which spontaneously changed to a sinus rhythm ten hours after the end of the operation. No clinical or laboratory findings indicated a cardiac ischemia and an additional Holter ECG-Recording showed no further cardiac arrhythmias. No other complications occurred afterwards and the patient was discharged after two weeks. This case report demonstrates clearly that despite a reduced rate of cardiovascular complications compared to other types of antidepressants selective serotonin reuptake inhibitors can lead to perioperative cardiac arrhythmias.

Publication Types:
  • Case Reports

PMID: 11324355 [PubMed - indexed for MEDLINE]


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