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In the future, scientists may bathe worms in drugs other than Prozac. Blakely, for example, plans to expose C. elegans to antipsychotic drugs that affect transporters for the brain chemical dopamine.

"Drugs have historically been effective tools for investigating how worm neurons work; worm neurons may prove equally effective for investigating how drugs work," notes William R. Schafer of the University of California, San Diego in a commentary in the Sept. 3 CELL.

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