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The role of sertraline
in a patient with recurrent hyponatremia.
G, Kanfer SN, Catalano MC, Alberts VA.
Psychiatry and Behavioral Medicine, University of South Florida College
of Medicine, Tampa, USA.
A 75-year-old female with major
depression was admitted to the hospital on two separate occasions for
medical problems. During both her hospitalizations she was evaluated by
a psychiatrist and diagnosed with a major depressive episode. On both
admissions the antidepressant chosen to treat her depression was
sertraline. Each time the patient was treated with sertraline she
developed significant hyponatremia within 7 days of the initiation of
therapy. The case is presented and discussed, with special emphasis on
the prior reports of hyponatremia associated with sertraline use, and
the treatment alternatives.
- Case Reports
- Review of Reported Cases
PMID: 8832263 [PubMed -
indexed for MEDLINE]