British drug giant GlaxoSmithKline (GSK:NYSE 
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      conceded that its antidepressant Seroxat caused heightened suicidal 
      thinking in some young patients, but urged that nobody stop using it 
      before consulting with a doctor. 
      
The statement follows a recommendation from the U.K. government that 
      physicians stop prescribing the medication to people under 18. "It has 
      become clear that the benefits of Seroxat in children for the treatment of 
      depressive illness do not outweigh these risks," the government said. 
      
      
GlaxoSmithKline, 
      for whom Seroxat is its second-biggest drug, stressed that the effects 
      were found only in children and adolescents and said there's no good 
      evidence that it causes actual suicides. The drug is called Paxil in the 
      U.S. 
      "In our paediatric trials, which included over 1,000 patients treated 
      with paroxetine, not a single person committed suicide," the company said. 
      "However, in our pediatric trials for patients with depression we have 
      seen a difference between Seroxat and placebo in terms of suicidal 
      thinking or attempts, particularly in adolescents." 
      
"While we believe that today's move will inevitably limit the choices 
      available to doctors treating children and teenagers under 18 years with 
      major depressive disorder, and the conclusions we draw from the data 
      differ, we recognize the MHRA's decision for U.K. paediatric patients and 
      we will work with them to implement the changes as soon as possible."