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                | Prozac May Have Fueled 
                  Gunman's Rage The Associated 
                  Press, Wed 17 Apr 2002
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 CAMBRIDGE, 
                  Mass. (AP) — A man on trial for killing seven co-workers 
                  tripled his dosage of Prozac before the shootings, a move that 
                  may have heightened his rage and sparked the shooting spree, a 
                  defense psychiatrist testified Wednesday.
 
 Dr. Anthony 
                  Joseph said Michael McDermott suffers from paranoid 
                  schizophrenia and other mental disorders that made him unable 
                  to understand that what he was doing was wrong when he opened 
                  fire at Edgewater Technology on Dec. 26, 2000.
 
 Prosecutors contend McDermott killed his colleagues 
                  because he was angry over the company's decision to withhold 
                  some of his salary to pay back taxes.
 
 But Joseph said 
                  McDermott told him that he had increased his dosage of Prozac 
                  by Dec. 1, first from 70 milligrams per day to 140 milligrams, 
                  and then to 210 milligrams. Joseph said McDermott increased 
                  the dosage without his doctor's permission or advice.
 
 ``It's very possible that Prozac is the final piece of 
                  the puzzle that explains the level of rage and anger that 
                  allowed the killings to occur,'' Joseph said.
 
 Although 
                  Prozac acts as an antidepressant, potential side effects 
                  include restlessness, agitation, psychosis, rage, anger and 
                  violence.
 
 Joseph acknowledged he could not say to ``a 
                  reasonable degree of medical certainty'' what effect the 
                  increased dosage had on McDermott.
 
 On Thursday, 
                  prosecutors planned to cross-examine Joseph.
 
 Prosecutors also plan to call witnesses to support 
                  their theory that McDermott concocted an elaborate tale to 
                  make himself look insane to the jury.
 
 On the witness 
                  stand last week, McDermott, a 43-year-old software engineer, 
                  said he believed he killed Nazis — not his co-workers.
 
 He said St. Michael the Archangel appeared to him 
                  before the killings and told him he could prevent the 
                  Holocaust and earn a soul if he traveled back in time to 1940 
                  and killed Adolf Hitler and six German generals.
 
 In 
                  testimony Wednesday, a defense psychologist said that a 
                  psychological test he gave McDermott in November indicates he 
                  is not feigning symptoms of mental illness.
 
 Dr. 
                  Anthony Kalinowski said the test results showed an eccentric, 
                  depressed and angry man who blames others for his problems.
 
 McDermott has said he researched symptoms of mental 
                  illness for years so he could appear sane to doctors and so 
                  that he could get the types of antidepressants he preferred.
 
 Under cross-examination, Kalinowski acknowledged that 
                  McDermott's knowledge of the test could have improved his 
                  ability to manipulate the results.
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