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[Drug-induced
seizures]
[Article in Danish]
Reuther LO,
Pedersen ST, Ronn AM.
H:S Bispebjerg Hospital, Klinisk
Farmakologisk Enhed, og Laegemiddelstyrelsen, Institut for Rationel
Farmakoterapi.
Numerous drugs have been suspected to be
associated with the occurrence of epileptic seizures. Our information
retrieval, however, shows that drug-induced seizures are relatively
rare. The risk of seizure seems to be increased, also in patients who
are not predisposed to seizure, when taking clozapine, enflurane,
theophylline, foscarnet, ganciclovir, and ritonavir. The risk of seizure
is greatest in patients predisposed to seizure by use of conventional
antipsychotics, olanzapine, risperidone, bupropion, tricyclic
antidepressants/selective serotonin reuptake inhibitors, cyclosporin,
interferon, corticosteroids, propofol, imipenem, chloroquine, and
mefloquine. In case of suspicion of drug-induced seizures, reporting
should be made to the Danish Medicines Agency. If the drug has been on
the market less than two years, reporting is
mandatory.
Publication Types:
PMID: 12715674 [PubMed - indexed for
MEDLINE]
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