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Comment in:
Serotonin syndrome after
concomitant treatment with linezolid and
citalopram.
Bernard L, Stern R, Lew D, Hoffmeyer
P.
Division of Orthopaedic Surgery, Geneva University
Hospital, Geneva, Switzerland. louis.bernard@hcuge.ch
Linezolid,
a new synthetic antimicrobial, is an important weapon against
methicillin-resistant Staphylococcus aureus (MRSA). Although there are
reports of serotonin syndrome developing after concomitant use of
linezolid and the selective serotonin reuptake inhibitor paroxitene,
this report concerns a patient receiving citalopram who developed
thrombocytopenia, serotonin syndrome, and lactic acidosis and died
following long-term linezolid therapy.
PMID: 12715317 [PubMed -
indexed for MEDLINE]
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