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1: Hum Exp Toxicol. 2002 Aug;21(8):463-6.

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Venlafaxine poisoning complicated by a late rise in creatine kinase: two case reports.

Oliver JJ, Kelly C, Jarvie D, Denieul S, Bateman DN.

Scottish Poisons Information Bureau, NPIS Edinburgh, Royal Infirmary, UK. james.oliver@ed.ac.uk

Newer anti-depressants are often considered to be safer than more established anti-depressants. However, clinical experience of the effects of these agents in overdose is limited. Here, we present two cases of venlafaxine overdose that were complicated by a delayed rise in plasma creatine kinase. Although the clinical consequences were not serious, physicians should be alerted to the possibility of delayed rhabdomyolysis or serotonin syndrome in patients who have taken venlafaxine in overdose.

Publication Types:

• Case Reports

PMID: 12412641 [PubMed - indexed for MEDLINE]

Jan 29 2004 15:06:34