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Antidepressant discontinuation
(withdrawal) symptoms presenting as
'stroke'.
Haddad PM, Devarajan S, Dursun
SM.
Cromwell House, Mental Health Services of Salford,
UK.
We report two patients who developed a severe discontinuation
(withdrawal) reaction following stoppage of paroxetine and venlafaxine,
respectively. Neurological symptoms were prominent and neither patient
could walk unaided. Both patients feared they had suffered a 'stroke'
and arranged an emergency medical consultation. One patient was
correctly diagnosed, the antidepressant was recommenced and symptoms
resolved within 24 h. Failure to recognize the reaction resulted in the
other patient being referred to a neurologist, undergoing a computed
tomography brain scan and an electroencephalogram and remaining
symptomatic for over 8 weeks. Relevant pharmacological issues are
discussed. The cases illustrate the importance of patients and
clinicians being familiar with antidepressant discontinuation
symptoms.
Publication Types:
PMID: 11448088 [PubMed - indexed for
MEDLINE]
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