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Michelle Gill, MD* [MEDLINE LOOKUP] Frank LoVecchio, DO*‡ [MEDLINE LOOKUP] Brad Selden, MD*‡ [MEDLINE LOOKUP]

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Abstract

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Serotonin syndrome, a potentially fatal iatrogenic complication of psychopharmacologic therapy, is most commonly reported with combinations of serotonergic medications. Serotonin syndrome is characterized by alterations in cognition, behavior, autonomic, and central nervous system function as a result of increased postsynaptic serotonin receptor agonism. We present the first reported case of serotonin syndrome after a single dose of fluvoxamine in a pediatric patient after ingestion of a single supratherapeutic dose of fluvoxamine. [Gill M, LoVecchio F, Selden B: Serotonin syndrome in a child after a single dose of fluvoxamine. Ann Emerg Med April 1999;33:457-459.]

Publishing and Reprint Information

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• From the Emergency Medicine Residency Program, Maricopa Medical Center,^* and Samaritan Regional Poison Center, Phoenix Children’s Hospital,^‡ Phoenix, AZ.
• Received for publication May 29, 1998.
  
• Revisions received October 2 and November 25, 1998.
  
• Accepted for publication December 26, 1998.
  
• Address for reprints: Frank LoVecchio, DO, Department of Emergency Medicine, Maricopa Medical Center, 2601 E Roosevelt Street, Phoenix, AZ 85008;E-mail frankl@samaritan.edu.
  

• Copyright © 1999 by the American College of Emergency Physicians.
  

• 0196-0644/99/$8.00 + 0
  
• 47/1/96900