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[Toxicologic findings in suicide
with doxepin and paroxetine]
[Article in
German]
Musshoff F, Grellner W, Madea B.
Institut
fur Rechtsmedizin, Universitat Bonn.
A young nurse was found dead
in her flat. In chemical-toxicological analysis the following femoral
blood drug concentrations were determined: paroxetine 0.176 mg/l,
doxepine 82.12 mg/l, desmethyldoxepine 0.34 mg/l. Additionally the drug
concentrations were determined in various body fluids and organs. The
results of the described fatality are discussed. For interpretation of
toxicologic results in antidepressant fatalities ratios of parent drug
to metabolite and postmortem drug redistribution should be taken into
account.
Publication Types:
PMID: 10489589 [PubMed - indexed for
MEDLINE]
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