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[Tourette's syndrome and
antidepressant therapy: exacerbation of nervous tics with
paroxetine]
[Article in German]
Ruth U,
Mayer-Rosa J, Schlamp D, Freisleder FJ.
Heckscher-Klinik fur
Psychiatrie und Psychotherapie des Kindes- und Jugendalters des Bezirks
Oberbayern, Munchen.
One possible side effect of selective
serotonin re-uptake inhibitors (SSRI) is the exacerbation of nervous
tics in a 12-year-old boy treated with tiapride following prescription
of paroxetine for a depressive syndrome. Potential causal factors
include residual cholinergic activity of paroxetine, the observably
increased drive under paroxetine, metabolic properties, and protein
binding. The problem of side effects under selective serotonin re-uptake
inhibitors, as well as the issues of co-morbidity and co-medication in
the treatment of nervous tics and Tourette's Syndrome are
discussed.
Publication Types:
PMID: 10863766 [PubMed - indexed for
MEDLINE]
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