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Severe hepatotoxicity
with jaundice associated with paroxetine.
Odeh M,
Misselevech I, Boss JH, Oliven A.
Department of Internal
Medicine B and Pathology, Bnai Zion Medical Center, Haifa,
Israel.
Hepatotoxicity due to paroxetine, a selective serotonin
reuptake inhibitor, is very rare, and to the best of our knowledge, only
five cases of liver injury in association with paroxetine have
previously been reported in the medical literature. We describe the
clinical, biochemical, and pathological findings in a patient with
paroxetine hepatotoxicity, which was reversed after withdrawal of the
drug. The present case and the others previously reported suggest that
hepatotoxicity should be taken into account as a rare complication,
sometimes severe, that may occur with paroxetine.
Publication
Types:
PMID: 11513198 [PubMed - indexed for
MEDLINE]
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