Entrez PubMed Nucleotide Protein Genome Structure OMIM PMC Journals Books
 Search for
  Limits Preview/Index History Clipboard Details    
spacer gif About Entrez

Text Version

Entrez PubMed
Help | FAQ

PubMed Services
Journals Database
MeSH Database
Single Citation Matcher
Batch Citation Matcher
Clinical Queries

Related Resources
Order Documents
NLM Gateway
Consumer Health
Clinical Alerts
PubMed Central


1: Acta Clin Belg. 1996;51(3):184-6. Related Articles, Links

Nightmares and hallucinations after long-term intake of tramadol combined with antidepressants.

Devulder J, De Laat M, Dumoulin K, Renson A, Rolly G.

Department of Anesthesia and Pain Clinic Gent University Hospital, Belgium.

Tramadol is a weak opioid with effects on adrenergic and serotonergic neurotransmission that is used to treat cancer pain and chronic non malignant pain. This drug was initiated in association with paroxetine and dosulepine hydrochloride in a tetraparetic patient with chronic pain. Fifty-six days after initiation of the treatment the patient presented hallucinations that only stopped after the withdrawal of psycho-active drugs and tramadol. The case report questions the long term use of pain killers combined with psycho-active drugs in chronic non malignant pain, especially if pain is under control.

Publication Types:
  • Case Reports

PMID: 8766220 [PubMed - indexed for MEDLINE]