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1: J Child Adolesc Psychopharmacol. 2002 Fall;12(3):265-70. Related Articles, Links
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Neuroleptic withdrawal versus serotonergic syndrome in an 8-year-old child.

Godinho EM, Thompson AE, Bramble DJ.

Child and Adolescent Mental Health Services, Lincolnshire Healthcare NHS Trust, Lincoln, United Kingdom.

There appears to be considerable symptomatic overlap between neuroleptic withdrawal reactions and the serotonin syndrome. This case report is of an 8-year-old boy who developed symptoms compatible with both conditions while discontinuing pimozide and starting fluoxetine. It illustrates how the use of neuroleptic medication in young children is not without the risk of serious adverse drug events and can complicate diagnostic issues. This case report supports the suggestion that adverse drug reactions related to neuroleptics and serotonergic agents could be part of the same clinical and neurophysiological spectrum.

Publication Types:
  • Case Reports

PMID: 12427301 [PubMed - indexed for MEDLINE]