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Neuroleptic withdrawal
versus serotonergic syndrome in an 8-year-old
child.
Godinho EM, Thompson AE, Bramble
DJ.
Child and Adolescent Mental Health Services, Lincolnshire
Healthcare NHS Trust, Lincoln, United Kingdom.
There appears to
be considerable symptomatic overlap between neuroleptic withdrawal
reactions and the serotonin syndrome. This case report is of an
8-year-old boy who developed symptoms compatible with both conditions
while discontinuing pimozide and starting fluoxetine. It illustrates how
the use of neuroleptic medication in young children is not without the
risk of serious adverse drug events and can complicate diagnostic
issues. This case report supports the suggestion that adverse drug
reactions related to neuroleptics and serotonergic agents could be part
of the same clinical and neurophysiological spectrum.
Publication
Types:
PMID: 12427301 [PubMed - indexed for
MEDLINE]
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