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[A case of rare side effects of
certain antidepressive drugs]
[Article in
German]
Haenel T, Stockli HR, Truog P.
Because of a
depressive syndrome, a 39-year-old patient received 20 mg fluoxetine per
day. Approximately 4 weeks later, treatment with this drug was stopped
after the patient had complained of worsening tremor, particularly of
the upper extremities. In addition, accommodation difficulties and
problems with word-finding had appeared shortly before. The symptoms
became worse after fluoxetine had been discontinued. Treatment of the
side effects with piperiden and bromazepam brought about no real
improvement in the patient's condition. The passive tremor with a
frequency of approximately eight per second mainly suggests an
extrapyramidal-parkinsonian cause. Five weeks after treatment with
fluoxetine had been discontinued, owing to the persistence of the
depressive syndrome the patient received maprotiline and clomipramine by
infusion in a private hospital. After 2-3 days the patient complained of
headaches and had a slightly raised temperature. After 7 days
maprotiline and clomipramine were discontinued completely. During the
fever there was no leucocytosis, so that a drug fever was diagnosed.
These rare side effects are discussed.
Publication Types:
PMID: 7885518 [PubMed - indexed for
MEDLINE]
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