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Non-fatal mirtazapine
overdose.
Retz W, Maier S, Maris F, Rosler
M.
Department of Psychiatry, University of Wurzburg, Germany.
psychpol@mail.uni-wuerzberg.de
We report the case of intoxication
of a 41-year-old female patient suffering from major depression with
mirtazapine complicated by severe hypothermia. The patient was brought
to an intensive care unit 10 hours after intake of 1200 mg mirtazapine
and 20 mg lorazepam and laying outside at outdoor temperatures below 0
degree C. The mirtazapine plasma-level was 368 ng/ml still after 41
hours. Body temperature was reduced to 26 degrees C and rhabdomyolysis
due to hypothermia was observed. Cardial and respiratory function was
compromised and intubation was necessary. The patient recovered without
persisting somatic impairment.
Publication Types:
PMID: 9861579 [PubMed - indexed for
MEDLINE]
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