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Sustained release
bupropion overdose: an important cause of prolonged symptoms after an
overdose.
Jepsen F, Matthews J, Andrews
FJ.
Accident and Emergency Department, Whiston Hospital,
Prescot, UK. Intensive Care Department, Whiston Hospital.
The
case is reported of a patient who had taken a deliberate overdose of
sustained release bupropion. The patient suffered from prolonged
symptoms including seizures before fully recovering. The prescription of
bupropion is encouraged as an aid to smoking cessation and it is
probable that bupropion overdose will become more common. Emergency
departments need to be aware that patients taking an overdose of
sustained release bupropion may have a delayed onset and prolonged
course of symptoms. The pharmacology, clinical features, and treatment
of bupropion overdose are discussed.
PMID: 14623854 [PubMed - in
process]
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