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Zyban-- is there a cause for
concern?
Tracey JA.
Bupropion
hydrochloride is a monocyclic antidepressant which is used in a
slow-release formulation as a smoking cessation aid. Its side effects
include insomnia and dry mouth with seizures occurring in 1 in 1000
patients. In overdose, it can cause tachycardia, conduction defects and
convulsions. It is, however, effective in smoking cessation in
approximately 20% of patients and may be more effective if combined with
nicotine replacement therapy. The key question is whether the risks
associated with the drug are justified by the obvious benefits to health
from smoking cessation.
Publication Types:
- Editorial
- Review
- Review, Tutorial
PMID: 12904129 [PubMed - indexed for
MEDLINE]
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