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1: Addict Biol. 2003 Sep;8(3):359-62. Related Articles, Links

Bupropion-induced somnambulism.

Khazaal Y, Krenz S, Zullino DF.

Department Universitaire de Psychiatrie Adulte, Prilly, Lausanne, Switzerland.

Whereas there are some case reports of bupropion-induced vivid dreaming and nightmares, until now it has not been associated with somnambulism. A case is reported of a patient treated with bupropion as a smoking cessation medication, who developed somnambulism during nicotine withdrawal. Furthermore, the sleepwalking episodes were associated with eating behaviour. Amnesia was reported for all episodes. As, on one hand,bupropion is a noradrenergic and dopaminergic drug and nicotine withdrawal, on the other hand, is associated with alterations in monoaminergic functions, an interaction at the level of these neurotransmitters is suggested as the underlying mechanism.

Publication Types:
  • Case Reports

PMID: 13129839 [PubMed - indexed for MEDLINE]